Availability
Please contact us to check the availability
Specificity
Mixture of synthetic peptides 15 aa near C-terminus of the mature HBD-3 (LPKEEQIGKCSTRGR) and 13 aa of N-terminal MBD-3
Species reactivity
-
Product presentation
Synthetic peptide lyophilized from PBS pH 7.5 at 1 mg/ml
Product category
Control Peptide
Antibody's raised in
human and mouse synthetic peptides
Antibody's isotype
-
Antibody's clone
-
Product is supplied as
lyophilisate
Recommended concentration for use
-
Protein concentration
-
Positive control
-
Pretreatment
-
Tested applications
Control peptide for DEF03-A and DEF03-S antibodies
Recommended secondary reagent
none
Storage method
Store at -20'°C'
UniProt number
Go to UniProt/SwissProt
Litterature
1. Harder J., Bartels J., Christophers E., and J.-M. Schröder (1997) Antibacterial peptide specific for Gram-negative Bacteria / also effective for Candida albicans. Nature 387; 861ff 2. Bals R., Wang X., Meegalla R. L., Wattler S., et al. (1999) Mouse ß-Defensin 3 is an inducible antimicrobial peptide expressed in the epithelia of multiple organs. Infection and Immunity 67(7); 3542-3547. 3. Jia H.P., Schutte B.C., Schudy A., Linzmeier R., et al. (2001) Discovery of new human beta-defensins using a genomics-based approach. Gene 263(1-2);211-218. 4. Garcia J.R., Jaumann F., Schulz S., Krause A., et al. (2001) Identification of a novel multifunctional beta-defensin (human beta-defensin 3) with specific antimicrobial activity. Its interaction with plasma membranes of Xenopus oocytes and the induction of macrophage chemoattraction. Cell Tissue Res. 306(2); 257-264. 5. Harder J., Bartels J., Christophers E., and J.-M. Schröder (2001) Isolation and characterization of human beta-defensin-3, a novel human inducible peptide antibiotic. J. Biol. Chem. 276(8); 5707-5713.
Tips
Gentaur products are intended for in vitro research use only. They must not be used for clinical diagnostics and not for in vivo experiments in humans or animals.
Tissue
control
Description
Isotype or positive controls by peptides, antibodies and deactivated samples.human, mouse or other beta β- and alpha α- defensins are expressed by neutrophils ( α- ), lymphocytes and epithelial cells. DEFA DEFB genes defend the host against pathogens. GENTAUR supplies anti-defensins, monclonals, polyclonals antisera and recombinant DEFs or peptides of defensin.