Availability
Please contact us to check the availability
Specificity
Synthetic Human-ß-Defensin-2 (hBD-2): Gly-Ile-Gly-Asp-Pro-Val-Thr-Cys-Leu-Lys-Ser-Gly-Ala-Ile-Cys-His-Pro-Val-Phe-Cys-Pro-Arg-Arg-Tyr-Lys-Gln-Ile-Gly-Thr-Cys-Gly-Leu-Pro-Gly-Thr-Lys-Cys-Cys-Lys-Lys-Pro (MW 4328,2)
Species reactivity
-
Product presentation
Synthetic peptide lyophilized from acetic acid
Product category
Control Peptide
Antibody's raised in
Human, synthetic
Antibody's isotype
-
Antibody's clone
polyclonal
Product is supplied as
lyophilisate
Recommended concentration for use
-
Protein concentration
-
Positive control
-
Pretreatment
-
Tested applications
Control peptide
Recommended secondary reagent
none
Storage method
Store at -20'°C'
UniProt number
Go to UniProt/SwissProt
Litterature
1. Harder J., Bartels J., Christophers E., and J.-M. Schröder (1997) Antibacterial peptide specific for Gram-negative Bacteria / also effective for Candida albicans. Nature 387; 861ff 2. Hiratsuka T., Nakazato M., Date Y., Ashitani J., Minematsu T, Chino N., and S. Matsukura (1998) Biochem. Biophys. Res. Comm. (Pharmacol.) 249; 943 ff 3. Hoover D.M., Rajashankar K.R., Blumenthal R., Puri A., Oppenheimer J.J., Chertov O., and Lubkowski J. (2000) The structure of human beta-defensin-2 shows evidence of higher order oligomerization. J Biol Chem. 275(42):32911-8 4. Hiratsuka T, Mukae H, Iiboshi H, Ashitani J, Nabeshima K, Minematsu T, Chino N, Ihi T, Kohno S, Nakazato M (2003) Increased concentrations of human beta-defensins in plasma and bronchoalveolar lavage fluid of patients with diffuse panbronchiolitis.Thorax. 58(5):425-30.
Tips
Gentaur products are intended for in vitro research use only. They must not be used for clinical diagnostics and not for in vivo experiments in humans or animals.
Tissue
control
Description
Isotype or positive controls by peptides, antibodies and deactivated samples.human, mouse or other beta β- and alpha α- defensins are expressed by neutrophils ( α- ), lymphocytes and epithelial cells. DEFA DEFB genes defend the host against pathogens. GENTAUR supplies anti-defensins, monclonals, polyclonals antisera and recombinant DEFs or peptides of defensin.Peptides short amino acid chains or epitopes or blocking antagonists. The shortest peptides are dipeptides, consisting of 2 amino acids joined by a single peptide bond, followed by tripeptides, tetra peptides, ... till polypeptides that are long, continuous, and unbranched synthetic peptide chains. These biological oligomers and polymers can be Solid-phase peptide synthesis (SPPS), or in continue produced for custom peptide synthesis projects. The High-efficiency solid phase peptide synthesis (HE-SPPS) is give very low production costs.
Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.