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Human Serum albumin (HSA) synthetically modified at Lysine residues and converted to HSA-N(epsilon)-(Carboxymethyl)-Lysine
CML-HSA will be bound by most polyclonal AGE-antibodies and CML-specific monoclonal antibodies.
Protein solution (HSA-CML) dialysed against PBS, 0.08% NaN3** added
Antibody's raised in
Product is supplied as
Recommended concentration for use
IHC control, ELISA, WB, PAGE,
Recommended secondary reagent
Store at -20°C
Go to UniProt/SwissProt
1. Kilhovd B.K., Giardino I., Torjesen P.A., Birkeland K.I., Berg, T.J., Thornally P.J., Brownlee M., and Hanssen K.F. (2003) Increased serum levels of the specific AGE-compound methylglyoxal-derived hydroimmidazolone in patiens with type 2 diabetes. Metabolism 52(2); 163-167. 2. Cellek S., Qu W., Schmidt A.M., and Moncada S. (2004) Synergistic action of advanced glycation end products and endogenous nitric oxide leads to neuronal apoptosis in vitro: a new insight into selective nitrergic neuropathy in diabetes. Diabetologia 47(2); 331-339.
*Gentaur products are intended for in vitro research use only. They must not be used for clinical diagnostics and not for in vivo experiments in humans or animals.
Isotype or positive controls by peptides, antibodies and deactivated samples.Peptides short amino acid chains or epitopes or blocking antagonists. The shortest peptides are dipeptides, consisting of 2 amino acids joined by a single peptide bond, followed by tripeptides, tetra peptides, ... till polypeptides that are long, continuous, and unbranched synthetic peptide chains. These biological oligomers and polymers can be Solid-phase peptide synthesis (SPPS), or in continue produced for custom peptide synthesis projects. The High-efficiency solid phase peptide synthesis (HE-SPPS) is give very low production costs.
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.