NCC4 - Control Lysate

General information

NCC4 - Control Lysate
20 μg
Catalog no:
532 EUR

Additional extra details

  • Category

    Other Reagents

    Long description

    NCC-4 (also known as HCC-4) is a CC chemokine. It is a 97 amino acid protein. It exhibits less than 30% sequence identity to other CC chemokines. NCC-4 chemoattracts human monocytes and THP-1 cells. However it does not chemoattract resting lymphocytes or neutrophils. It has been found to supress proliferation of myeloid progenitor cells and induces calcium flux in THP-1 cells. This calcium flux can be desensitized by exposure to RANTES which suggests that NCC-4 and RANTES share the same receptor in THP-1 cells.

    Antibody come from

    Hybridoma produced by the fusion of splenocytes from mice immunized with protein preparation from a homogenate of a human mammary tumor and mouse myeloma cells.

  • Other description

    Provided as solution in phosphate buffered saline with 0.08% sodium azide.


    not specified

    Antigen-antibody binding interaction

    NCC4 - Control Lysate

  • Antibody is raised in

    see techfile

    Antibody's reacts with

    see techfile

    Antibody's reacts with these species

    This antibody doesn't cross react with other species

  • Antibody's specificity

    No Data Available


    Activity Assay

    Antibody's suited for

    Detects human tenascin protein by Western blot at 1-5 µg/ml. Can also be used for immunohistochemistry on frozen and paraffin-embedded tissue sections and for immunoprecipitation. Optimal concentration should be evaluated by serial dilutions.

  • Storage


    Relevant references

    1. Verstraeten, A.A. et al. Tenascin expression in basal cell carcinoma. Br. J. Dermatol. 1992, 127, 571-574_x000B__x000B_2. Le Poole, I.C., et al. Tenascin is overexpressed in vitiligo lesional skin and inhibits melanocyte adhesion. Br. J. Dermatol. 1997, 137, 171-178_x000B__x000B_3. Rulo, H.F., et al. Normal human skin demonstrates marked site-variation of tenascin expression, not correlated to epidermal proliferation (Ki-67 binding). J. Dermatol. Sci. 1993, 5, 54-57

    Protein number

    see ncbi

  • Warnings

    This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals. This datasheet is as accurate as reasonably achievable, but Nordic-MUbio accepts no liability for any inaccuracies or omissions in this information.




    Isotype or positive controls by peptides, antibodies and deactivated samples.