MCP-1 - Control Lysate

General information

MCP-1 - Control Lysate
20 μg
Catalog no:
532 EUR

Additional extra details

  • Category

    Other Reagents

    Long description

    Monocyte chemotactic protein (MCP-1) is also known as monocyte chemotactic and activating factor (MCAF). It is the product of the human JE gene. The precursor form of MCP-1 consists of 99 amino acids with a signal peptide sequence consisting of 23 amino-terminal amino acids. The mature form of MCP-1 has 4 cysteine residues. The first two cysteine residues are in an adjacent position C-C, which characterizes MCP-1 as a member of the chemokine subfamily. MCP-1 is a nonglycosylated protein consisting of 76 amino acids with a molecular weight of 8700 daltons. MCP-1 mRNA expression can be induced in monocytes/macrophages, B lymphocytes, endothelial cells and astrocytoma cells by LPS. IL-1 will induce production of MCP-1 in fibroblasts, keratinocytes, hepatoma cells, and Type II pneumocytes. In vitro, MCP-1 will act on monocytes to initiate chemotaxis, induce superoxide anion release, induce the release of lysosomal enzymes and augment cytostatic activity. In vivo, MCP-1 will induce macrophage infiltration. The MCP-1 gene contains potential binding sites for several transcription factors, including AP-1, AP-2, NF-kB, and NF-IL6.

    Antibody come from

    Hybridoma produced by the fusion of splenocytes from mice immunized with purified human keratin 7 isolated from HeLa cytoskeleton and mouse myeloma cells.

  • Other description

    Provided as solution in phosphate buffered saline with 0.08% sodium azide.


    not specified

    Antigen-antibody binding interaction

    MCP-1 - Control Lysate

  • Antibody is raised in

    see techfile

    Antibody's reacts with

    see techfile

    Antibody's reacts with these species

    This antibody doesn't cross react with other species

  • Antibody's specificity

    No Data Available


    Activity Assay

    Antibody's suited for

    Detects keratin 7 by Western blot. Detects a 54 kDa band corresponding to keratin 7. Optimal concentration should be evaluated by serial dilutions.

  • Storage


    Relevant references

    1. Neoplasma 1990, 37, 333-342_x000B__x000B_2. J. Tumor Marker Oncol. 1990, 5, 219_x000B__x000B_3. Int. J. Cancer 1988, Suppl. 3, 50-55

    Protein number

    see ncbi

  • Warnings

    This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals. This datasheet is as accurate as reasonably achievable, but Nordic-MUbio accepts no liability for any inaccuracies or omissions in this information.




    Isotype or positive controls by peptides, antibodies and deactivated samples.