FtsH2, FtsH2 positive control/quantitation standard

General information
 

Name:
FtsH2, FtsH2 positive control/quantitation standard
Size:
250 µl
Catalog no:
AS11 1789S
Price:
395 EUR
 

Additional extra details
 

  • Available ordering format

    Lyophilized

    Immunogen

    to be determined

    Raised in

    N/A

  • Clonality

    N/A

    Clone

    N/A

    Purification

    Affinity purified

  • How to reconstitute

    For reconstitution add 225 µl of sterile water.

    Storage condition

    store lyophilized/reconstituted at -20°C; once reconstituted make aliquots to avoid repeated freeze-thaw cycles. Please, remember to spin tubes briefly prior to opening them to avoid any losses that might occur from lyophilized material adhering to the cap or sides of the tubes.

    Verified applications

    western blot (WB)

  • Connected products

    AS11 1789 | anti-FtsH1-11 | ATP-dependent zinc metalloprotease FtsH1-11AS16 3930 | anti-FtsH1 + FtsH5 | ATP-dependent zinc metalloprotease FtsH1 + FtsH5 (chloroplastic)AS16 3929 | anti-FtsH2 + FtsH8 | ATP-dependent zinc metalloprotease FtsH2 + FtsH8 (chloroplastic)AS07 204 | anti-FtsH3 + FtsH10 | ATP-dependent zinc metalloprotease FtsH3 + FtsH10 (mitochondrial)AS07 205 | anti-FtsH4 | ATP-dependent zinc metalloprotease FtsH4 (mitochondrial)AS05 094A | anti-FtsH6 | ATP-dependent zinc metalloprotease FtsH6 (chloroplastic)AS06 130 | anti-FtsH9 | ATP-dependent zinc metalloprotease FtsH9 (chloroplastic)AS07 251 | anti-FtsH10 | ATP-dependent zinc metalloprotease FtsH10 (mitochondrial)Antibodies to other proteins involved in photosynthesisPlant protein extraction bufferSecondary antibodies

    Recommended dilutions for use

    Standard curve: 3 loads are recommended (0.5, 2 and 4μl).For most applications a sample load of 0.2μg of chlorophyll will give a FtsH2 signal in this range.Positive control: load per well: a 2μl load is optimal for most chemiluminescent detection systems.This standard is stabilized and ready and does not require heating before loading on the gel. Please note that this product contains 10% glycerol and might appear as liquid but is provided lyophilized. Allow the product several minutes to solubilize after adding water. Mix thoroughly but gently Take extra care to mix thoroughly before each use, as the proteins tend to settle with the more dense layer after freezing.

    Molecular weight (expected | аpparent)

    75 kDa

  • Verified reactivity

    to be determined

    Possible reactivity

    to be determined

    No reactivity

    to be determined

  • Supplementary information

    Concentration: after adding 225 µl of sterile milliQ water final concentration of the standard is 0.1 pmoles/µlThis standard is ready-to-load and does not require any additions or heating. It needs to be fully thawed and thoroughly mixed prior to using. Avoid vigorous vortexing, as buffers contain detergent. Following mixing, briefly pulse in a microcentrifuge to collect material from cap.Please note that this product contains 10% glycerol and might appear as liquid but is provided lyophilized. Allow the product several minutes to solubilize after adding water. Mix thoroughly but gently Take extra care to mix thoroughly before each use, as the proteins tend to settle with the more dense layer after freezing.

    References

    to be added when available, antibody released in October 2011.

    Scientific context

    FtsH belong to a family of ATP dependent peptidases. Localized in a chloroplast are following isoforms: FTSH1 (synonymes AAA, FTSH, FTSH Protease 1), Ftsh2 (VAR2, VARIEGATED 2), FtsH5 (VAR1, VARIEGATED 1), FtsH6 (FTSH PROTEASE 6), FtsH7, FtsH8. FtsH9.Localized in mitochondria are following isoforms: FtsH3 (FTSH Protease 3), FtsH4, FtsH10, FtsH11.

  • Notes

    The FtsH2 protein standard can be used in combination with anti-FtsH2 antibodies to quantitate FtsH2 from a range of cyanobacteria. Global antibodies are raised against highly conserved amino acid sequences in the FtsH protein.Quantitative western blot: detailed method description, video tutorial

    Protein number

    Refer to NCBI

    TAIR number

    Refer to NCBI

  • Tissue

    control

    Description

    Isotype or positive controls by peptides, antibodies and deactivated samples.Positive controls are the same as the target vector or antibody or protein and can be spiked to the sample before the analysis starts.

    Group

    positif