PEPC, phosphoenolpyruvate carboxylase positive control/quantitation standard

General information
 

Name:
PEPC, phosphoenolpyruvate carboxylase positive control/quantitation standard
Size:
100 µl
Catalog no:
AS09 458S
Price:
295 EUR
 

Additional extra details
 

  • Available ordering format

    Inquire

    Immunogen

    to be determined

    Raised in

    N/A

  • Clonality

    N/A

    Clone

    N/A

    Purification

    Affinity purified

  • How to reconstitute

    For reconstitution add 90 µl of milliQ water. Please notice that this product contains 10% glycerol and might appear as liquid but is provided lyophilized.

    Storage condition

    store lyophilized/reconstituted at -20°C; once reconstituted make aliquots to avoid repeated freeze-thaw cycles. Please, remember to spin tubes briefly prior to opening them to avoid any losses that might occur from lyophilized material adhering to the cap or sides of the tubes.

    Verified applications

    western blot (WB)

  • Connected products

    AS09 458 | anti-PEPC | phosphoenolpyruvate carboxylase, rabbit antibodyAS07 241 | anti-PEPCK | PEP carboxy kinase

    Recommended dilutions for use

    Standard curve: 3 loads are recommended (0.5, 2 and 4μl).For most applications a sample load of 0.2 μg of chlorophyll/well will give a RbcL signal in this range.Positive control: a 2 μl load per well is optimal for most chemiluminescent detection systems. Higher standard concentration needs to be used to allow detection by Coomasie stains. Such gels with higher standard concentration can not be used for quantitation using chemiluminescence.This standard is stabilized and ready and does not require heating before loading on the gel. Please note that this product contains 10% glycerol and might appear as liquid but is provided lyophilized. Allow the product several minutes to solubilize after adding water. Mix thoroughly but gently Take extra care to mix thoroughly before each use, as the proteins tend to settle with the more dense layer after freezing.

    Molecular weight (expected | аpparent)

    110 | 105 kDa

  • Verified reactivity

    to be determined

    Possible reactivity

    to be determined

    No reactivity

    to be determined

  • Supplementary information

    Concentration: after re-constitution with sterile milliQ water final concentration of the standard is 0.15 pmoles/µlProtein standard buffer composition: Glycerol 10%, Tris Base 141 mM, Tris HCl 106 mM, LDS 2%, EDTA 0.51 mM, SERVA® Blue G250 0.22 mM, Phenol Red 0.175 mM, pH 8.5, 0.1mg/ml PefaBloc protease inhibitor (Roche), 50 mM DTT.This standard is ready-to-load and does not require any additions or heating.This standard is stabilized and ready and does not require heating before loading on the gel. Please note that this product contains 10% glycerol and might appear as liquid but is provided lyophilized. Allow the product several minutes to solubilize after adding water. Mix thoroughly but gently Take extra care to mix thoroughly before each use, as the proteins tend to settle with the more dense layer after freezing.

    References

    to be added when available, product released in October 2014.

    Scientific context

    Phosphoenolpyruvate carboxylase (PEPC; EC 4.1.1.31) serves as an important control element in the regulation of photosynthetic carbon metabolism in C4 and CAM plants. This is the first enzyme of the pathway, and PEPC enzymes are encoded by a small multigenic family. Several isoforms of PEPC have been characterised in maize, sorghum and sugarcane. These isoforms are involved in several functions such as the initial fixation of atmospheric CO2 (= C4 PEPC) and anaplerotic functions associated with nitrogen assimilation or amino acid biosynthesis (Lepiniec et al. 1994).

  • Notes

    The PEPC protein standard can be used in a combination with Agrisera global PEPC antibiody to quantitate PEPC from a wide range of species. Global antibodies are raised against highly conserved amino acid sequence. Quantitative western blot: detailed method description, video tutorial

    Protein number

    Refer to NCBI

    TAIR number

    Refer to NCBI

  • Tissue

    control

    Description

    Isotype or positive controls by peptides, antibodies and deactivated samples.Positive controls are the same as the target vector or antibody or protein and can be spiked to the sample before the analysis starts.

    Group

    positif