GlnA, glutamine synthetase positive control/quantitation standard

General information
 

Name:
GlnA, glutamine synthetase positive control/quantitation standard
Size:
250 µl
Catalog no:
AS09 018S
Price:
395 EUR
 

Additional extra details
 

  • Available ordering format

    Lyophilized

    Immunogen

    to be determined

    Raised in

    N/A

  • Clonality

    N/A

    Clone

    N/A

    Purification

    Affinity purified

  • How to reconstitute

    For reconstitution add 225 µl of milliQ water

    Storage condition

    store lyophilized/reconstituted at -20°C; once reconstituted make aliquots to avoid repeated freeze-thaw cycles. Please, remember to spin tubes briefly prior to opening them to avoid any losses that might occur from lyophilized material adhering to the cap or sides of the tubes.

    Verified applications

    Western blot (WB)

  • Connected products

    collection of other protein standardsAS01 018 | anti-GlnA | glutamine synthetase hen antibodycollection of other global antibodiescollection of antibodies to proteins involved in nitrogen metabolismPlant and algal protein extraction bufferSecondary antibodies

    Recommended dilutions for use

    Standard curve: 3 loads are recommended (0.5, 2 and 4μl).For most applications a sample load of 0.2μg of chlorophyll will give a GlnA signal in this range.Positive control: a 2μl load per well is optimal for most chemiluminescent detection systems. This standard is stabilized and ready and does not require heating before loading on the gel.Please note that this product contains 10% glycerol and might appear as liquid but is provided lyophilized. Allow the product several minutes to solubilize after adding water. Mix thoroughly but gently Take extra care to mix thoroughly before each use, as the proteins tend to settle with the more dense layer after freezing.

    Molecular weight (expected | аpparent)

    in most gel systems GlnA migrates around 53 kDa

  • Verified reactivity

    to be determined

    Possible reactivity

    to be determined

    No reactivity

    no confirmed exceptions from predicted reactivity known in the moment

  • Supplementary information

    Concentration: after adding 225 µl of milliQ water final concentration of the standard is 0.20 pmol/µlProtein standard buffer composition: Glycerol 10%, Tris Base 141 mM, Tris HCl 106 mM, LDS 2%, EDTA 0.51 mM, SERVA® Blue G250 0.22 mM, Phenol Red 0.175 mM, pH 8.5, 0.1mg/ml PefaBloc protease inhibitor (Roche), 50mM DTT.This standard is ready-to-load and does not require any additions or heating. It needs to be fully thawed and thoroughly mixed prior to using. Avoid vigorous vortexing, as buffers contain detergent. Following mixing, briefly pulse in a microcentrifuge to collect material from cap.This standard is stabilized and ready and does not require heating before loading on the gel. Please note that this product contains 10% glycerol and might appear as liquid but is provided lyophilized. Allow the product several minutes to solubilize after adding water. Mix thoroughly but gently Take extra care to mix thoroughly before each use, as the proteins tend to settle with the more dense layer after freezing.

    References

    to be added when available

    Scientific context

    Glutamine synthetase (GlnA) is the key enzyme in the incorporation of mineral nitrogen into glutamine.This product is a recombinant GlnA protein standard, source Synechocystis strain PCC 6803.

  • Notes

    The GlnA protein standard can be used in combination with global anti-GlnA antibodies to quantitate GlnA from a wide range of species. Global antibodies are raised against highly conserved amino acid sequences in the GlnA protein.Quantitative western blot: detailed method description, video tutorial

    Protein number

    Refer to NCBI

    TAIR number

    Refer to NCBI

  • Tissue

    control

    Description

    Isotype or positive controls by peptides, antibodies and deactivated samples.Positive controls are the same as the target vector or antibody or protein and can be spiked to the sample before the analysis starts.

    Group

    positif